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A: For chronic in vivo studies, daily administration of a specific 5-Amino-1MQ dosage is common to maintain consistent systemic exposure

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Patients were randomly assigned to undergo wide excision with margins of 2 cm (n = 476) or 5 cm (n = 513).[3][Level of evidence A1] With a median follow-up of 11 years, there was no statistically significant difference in OS between the two groups