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Moreover, the imbalance in microbiota composition skews immune cell differentiation toward pro-inflammatory phenotypes, particularly Th 1 and Th 17 cells, and concurrently diminishes the function and numbers of regulatory T cells, thereby enhancing the risk and severity of autoimmune thyroid diseases (Takiishi et al., 2017)

Effects: Excessive weight loss, gastrointestinal discomfort

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Treatment of actinic keratosis may include the following: Topical chemotherapy

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Correct storage reduces contamination risks during ongoing medication usage