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In contrast, phentermine is approved to manage weight in adults and children ages 17 and older with obesity or who are overweight with weight-related conditions

Thornton, 2013)

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Furthermore, altered expression and activation of proinflammatory genes (eg IL-1 receptor family and genes regulating fibrotic responses ( TGF beta-1 , FGFR2 receptor 2 ) that may contribute to the development of NASH are also under the control of TH

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