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F1000Research, 9, F1000 Faculty Rev-239

It also has documented activity at CD36, a scavenger receptor involved in fatty acid uptake and inflammatory signaling

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Additionally, increased ChaC2 expression targets the Cadherin 1 gene (encoding E-cadherin) mutation, resulting in E-cadherin loss, increased epithelial-mesenchymal transformation and lymph node metastasis, ultimately contributing to the low differentiation of breast cancer (50)