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The study has the following limitations: (1) underreporting and selection bias in FAERS data,as it lacks a comprehensive list of concomitant medications, which may lead to biased analysis results

Clinical trials show approximately 50% of lost weight returns within 12 months after discontinuation, though individual results range from 20% to 100% regain

As a result, the isotopic AST converted to (3 R ,3 R )-meso, and (3 S ,3 S )-isomers at an approximate ratio of 1:2:1

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The choice depends on individual health goals and needs