The augmented proliferative activity is concomitant with heightened vulnerability to superficial skin infections and tissue injury (Farkas and Kemeny 2013)
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Further, NICE and the BNF says that if there are neurological symptoms present, then every other day injections are the recommended treatment, so all the points you make about B12 being stored and sufficient are not really relevant
The agency was in agreement with PDS concerns and warned that using injectable glutathione for skin lightening can pose serious health risks, including toxicity to the liver, kidneys, and nervous system, as well as the possibility of Stevens-Johnson Syndrome, a rare but life-threatening skin reaction
Dietary deficiency Vegans can develop vitamin B12 deficiency because vitamin B12 is most often found in animal products
Key Nutrients for Enhanced Recovery 1