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Although endothelial activation and redox signaling compose a normal host defense, when this activation is sustained, chronic production of ROS may exceed the capacity of cellular enzymatic and nonenzymatic antioxidant defenses [49], contributing to triggering vascular diseases such as atherosclerosis or peripheral artery disease [102, 103]

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Accessed 20 Nov 2021 Page MJ, McKenzie JE, Bossuyt PM et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

* Has strong antioxidant action , protecting cells from damage caused by free radicals Supports the detoxification of the body by aiding in the removal of heavy metals and toxins

Am J Physiol (1987) 252(1 Pt 2):R1605

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