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In naturally aged mice, FOXO4-DRI improved the testicular microenvironment and alleviated age-related testosterone secretion insufficiency with decreased p53, p21, and p16 protein levels in treated testes compared to aged controls
or inability to detoxify after exposure to free radicals, such as feeling groggy or achy after exercise, or being exposed to pollution
Consequently, it seems that the most lucrative application of antimicrobial peptides and proteins is a local treatment rather than a systemic application
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Oxidative stress is one of the main features of septic patients, so antioxidants can be a good alternative treatment