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Other studies have reported that drug side effects are related individuals with low-activity of CYP2D6 (EM/IM category, comprising the following genotypes: *2/*9, *1/*10, *1/*41, *2/*41, *2/*35, *35/*35, and *35/*41 ) displaying an increased induction of plasma hypo-osmolality, hyponatremia, and increased plasma antidiuretic hormone (vasopressin) after MDMA consumption (Aitchison et al., 2012)

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