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AG924005: β-D-Lac-Ethyl-Azide (Peracetate) Pack Size:100 mg α2-3 sialosides are ligands for

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Description

α2-3 sialosides are ligands for selectins and certain Siglecs

22 / An α-D-galactose ligand equipped with an azide-functionalized linker through a short ethyl spacer

Fmoc-Thr((Ac)3-β-L-Rha)-OH

55 / An A2 biantennary disialo (α2-6) N-glycan equipped with a biotin tag through a 6-aminohexanoic acid spacer

N-α-Fmoc-O-(2

AG924005: β-D-Lac-Ethyl-Azide (Peracetate) Pack Size:100 mg α2-3 sialosides are ligands forC28H39N3O18 705. 6 A peracetylated D lactose ligand equipped with an azide functionalized linker through a short ethyl spacer. The terminal azide can be covalently coupled to alkyne partners via copper catalyzed azide alkyne cycloaddition (CuAAC), or to dibenzocyclooctyne (DBCO) and related strained alkynes using copper free click chemistry, forming stable 1,2,3 triazole linkages. The sugar hydroxyl groups are protected as acetate esters (peracetate);

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