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However, after GLP-1RAs treatment, the joint structural damage was significantly alleviated and osteophyte formation was reduced (Fig

doi: 10.1111/DOM.14997 31 MaXLiuZIlyasILittlePJKamatoDSahebkaAet al

GLP-1 receptor agonistsincluding semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)commonly affect bowel movements, though responses vary widely among patients

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Not candidates: anyone with a personal or family history of medullary thyroid carcinoma or MEN-2 syndrome, anyone with active pancreatitis, anyone currently pregnant or trying to conceive, anyone under 18

It was suggested that this was achieved by inhibiting the production of pro-inflammatory cytokines and reducing the increase in intestinal permeability (102)