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Why a Compounding Pharmacy May Be Central in MCAS Care Many medications used in Mast Cell Activation Syndrome management fall into one of three categories: Not commercially available in appropriate oral form (e.g., ketotifen) Available only in fixed strengths that limit gradual titration Contain excipients that may trigger symptoms in sensitive patients Because of these limitations, compounding pharmacies may becomes integral to executing a layered MCAS therapy plan

doi: 10.3389/fonc.2023.1216911 Received 04 May 2023 Accepted 17 July 2023 Published 03 August 2023 Volume 13 - 2023 Edited by Arthur Sun Myint, Clatterbridge Hospital, United Kingdom Reviewed by Joji Kitayama, Jichi Medical University, Japan

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