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In the journal Nature this week it was shown that inflamed gut-derived CD4+ T cells can infiltrate the brain, leading to neuroinflammation and neurological damage in the experimental model

This unique ability to target two receptors may explain why tirzepatide can be more effective than other GLP-1 medications at both improving blood sugar levels and weight loss

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This contrasts with medications that dont follow simple half-life elimination, where clearance timelines might be more variable and harder to predict

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