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Weight should be monitored and a flexible-dosing approach could be employed to mitigate unintended weight loss [127]
Healthy kidney function is typically defined by an estimated glomerular filtration rate (eGFR) above 90 mL/min/1.73m without evidence of kidney damage, whilst chronic kidney disease (CKD) is classified into stages based on declining eGFR values and the presence of albuminuria, as outlined in NICE guideline NG203
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In addition, cytokine, including HSP70i, IL-15, IL-17/23, TNF as well as wnt signaling pathway, Tregs, miRNAs have also been proved to be involved in the pathogenesis of vitiligo
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