Safety, tolerability, pharmacodynamics and pharmacokinetics of albiglutide, a long-acting glucagon-like peptide-1 mimetic, in healthy subjects
Contrast sensitivity (MARS) was intact at 1.64 logCS in each eye
A recent retrospective cohort also observed that, even in overweight patients without diabetes, the risk of primary open-angle glaucoma and ocular hypertension were significantly lower in the GLP-1RA group at both 3 and 5 years of follow-up (Vasu et al., 2025), suggesting the benefit of GLP-1RAs in the eye as an independent factor apart from blood glucose control
GI effects are common
Anytime you microdose you run the risk of not putting enough of a drug in your system to get its benefits, but experimenting with lower doses may also come with upsides, including fewer side effects
Both are GLP-1 receptor agonists that reduce appetite and support weight loss