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It is the only peptide in this class with human clinical data: the NERVARA trial (Phase 2, NCT02039687) studied its effect on diabetic neuropathy

Chilling injury resulting from LT stress is associated with disparity between making and elimination of ROS

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Conversely, ROS produced via NADPH oxidase can exacerbate ER dysfunction, suggesting a reciprocal relationship between oxidative and protein-folding stress (Uzilday et al

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