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This synergistic combination is why it outperformed earlier GLP-1 monotherapies like semaglutide

approval is expected in 2026

Who should avoid taking GLP-1 medications

GLP-1 receptor agonist drugs (called GLP-1s for short) like semaglutide work by mimicking this hormone, increasing insulin release (which helps control diabetes), signaling your brain that you're full, and slowing digestion

As our knowledge of GLP-1 biology advances and novel therapeutic innovations arise, these agents are expected to assume a progressively pivotal role in the management of metabolic disorders and their related complications, ultimately enhancing patient outcomes across various disease states

Together these produce a stronger and longer-lasting effect from the same amount you previously tolerated