Kannan S, Muthusamy VR, Whitehead KJ, Wang L, Gomes AV, Litwin SE, Kensler TW, Abel ED, Hoidal JR, Rajasekaran NS (2013) Nrf2 deficiency prevents reductive stress-induced hypertrophic cardiomyopathy
This mechanism makes it easier to consume fewer calories and adhere to a reduced-calorie diet
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Its a simple concept, but its execution is what separates a successful study from a failed one