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This represents the first time a medication for weight loss also can significantly reduce a patients MACE risk

H., Newman, S

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Thereby, PI3K and AKT transcription was downregulated 1.7- and 2-fold, respectively, whereas PGC-1 transcripts were increased 7-fold and AKT phosphorylation was reduced by 3550%

Shanahan F, Ghosh TS, OToole PW