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These molecules are very toxic to the cell

Immunohistochemistry of brain tissues from mice treated with GHK showed evidence of decreased inflammation and increased labeling of histone deacetylase 2, suggesting that in addition to an anti-inflammatory effect, GHK may be triggering an epigenetic pathway in the amelioration of cognitive impairment in aging mice

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The end result is similar: channels for topical absorption, growth factor release, and wound healing response

Proc Natl Acad Sci USA 2015 Aug 17