glp-1 and ms The Role of Glucagon-Like Peptide-1 Agonists in the Treatment of Multiple Sclerosis: A Narrative Review GLP-1s and Multiple Sclerosis -

Safety Comparison# Key Differences Summary# Weight loss : Comparable (~20-21%), no head-to-head trial Mechanism : Amylin/GLP-1 (CagriSema) vs GIP/GLP-1 (tirzepatide) Molecules : Two-peptide combination vs single dual-agonist molecule Approval : Tirzepatide is FDA-approved

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The SURMOUNT-1 trial showed participants losing up to 22.5% of their body weight on the highest dose, compared to approximately 15-17% with semaglutide in the STEP trials

Ideally, this should be spread throughout the day to ensure protein intake at each meal and snack

Joo HS, Suh JH, Lee HJ, Bang ES, Lee JM