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Fentanyl is 50x more potent than heroin, and accidental overdoses are common even among experienced drug users

Only samples that show positive response to at least 1 positive control (70 mM KCl or 10 M IBMX/FSK) were included in analysis

A titration tolerability study (PMC) found that patients who followed the standard titration protocol had meaningfully better tolerability outcomes than those who escalated faster

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Perez further stated the importance of staying well hydrated, explaining that when peoples appetites are suppressed, they often tend to reduce their fluid intake as well

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