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Tirzepatide's dual-action mechanism produces greater results than semaglutide alone with clinical trial data showing an average of 22.5% body weight loss

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Participants were also advised to follow a reduced-calorie diet and increased physical activity , so the results reflect medication plus lifestyle changes, not semaglutide alone

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Heres why: Protein can help prevent the loss of muscle mass and is essential for maintaining muscle strength, bone health and blood sugar control

This finding aligns with current AAFP clinical guidance recommending oral therapy as a first-line option for most patients