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Supports fat burning: Encourages the use of stored fat as fuel

In an open-label, phase 3, multicenter study involving 11 children aged 25 years with biallelic POMC, PCSK1, or LEPR variants, or genetically confirmed BardetBiedl syndrome (BBS), 83% achieved a 0.2-point reduction in BMI Z score over 52 weeks, with a mean BMI reduction of 18% observed overall (26% in the POMC/LEPR group and 10% in the BBS group) [45]

However, no GLP-1RAs are currently approved for children younger than six, representing a therapeutic gap

Animal Physiology Animal Nutr

For example, type 2 diabetes that is currently in remission despite a prior diagnosis could still fall in this category in the poll data

Mast cell-mediated local passive allergic reactions in mice were assessed following treatment with 10 mg/kg or 20 mg/kg pterostilbene [209]