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Its possible the added glucagon agonism helps with energy expenditure, allowing people to burn more calories, on top of the appetite suppression

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All Paragon compounds undergo third-party analytical testing to verify purity, identity, and consistency

doi: 10.1152/japplphysiol.00209.2017 151 PereiraSParkEMooreJFaubertBBreenDMOprescuAIet al

The article points to people with a personal or family history of migraines, baseline hypertension, or dehydration-sensitive conditions