should i do tirzepatide or semaglutide vs for Weight Loss Tirzepatide vs. Semaglutide for Weight

GLP-1 directly activates anorexigenic POMC and CART neurons and indirectly inhibits, via GABAergic transmission, orexigenic NPY and AgRP neurons [39]

After significant weight loss, your resting metabolic rate drops slightly more than body-size change alone would predict, an effect called metabolic adaptation 8

These were predominantly mild to moderate, transient, and most frequent during dose escalation

Withholding is generally only necessary in selected high-risk cases or for patients with significant gastrointestinal symptoms

If you already take medication for high blood pressure, your readings should be monitored during treatment

Elsevier, pp 2737