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10.3389/fneur.2022.905640 123 WangW.WangY.WangF.XieG.LiuS.LiZ.et al (2024a)

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Research Rationale GHK-Cu stimulates collagen Type I and III synthesis and promotes fibroblast proliferation BPC-157 drives VEGF-dependent angiogenesis to supply the repair site GHK-Cu modulates matrix metalloproteinase (MMP) activity for controlled ECM remodelling BPC-157 regulates inflammatory cytokine expression and protects endothelial integrity The copper-peptide has documented antioxidant and anti-inflammatory properties that complement BPC-157's effects on growth factor signalling and cell survival pathways Each compound is individually vialled with independent COAs customise concentrations independently for your specific assay Research Applications Applied in dermal fibroblast culture models, wound healing scratch assays, collagen synthesis quantification (hydroxyproline assay), endothelial tube formation assays, and MMP activity studies