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The reconstituted solution should be stored at 2C to 8C for short-term use or frozen for long-term stability

It modulates iron levels by inducing ferritin expression, thereby limiting iron-catalysed free radical generation

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The reconstitution process involves slowly adding bacteriostatic water to the vial with the lyophilisate, most often along the vessel wall, in order to avoid foaming and degradation of the peptide

Therapeutic strategy focusing on the ferroptosis pathway SLC7A11, a molecule that protects cancer cells from ferroptosis-induced cell death, is overexpressed in different types of cancers, including ovarian cancer, lung cancer, triple-negative breast cancer, PDAC, renal cell carcinoma, liver cancer, and glioma, and it is associated with aggressive phenotypes and poor prognosis [16,46,89]

Together, they build a fibrocartilaginous bridge across the fracture gap called a soft callus