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Mitochondrial fission, fusion and stress

So, what does this mean for patients

If the molecule is broken down into its base amino acids, it loses its unique "master antioxidant" power

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GLP-1R activates the PI3K/Foxo1 pathway to promote -cell survival, and can also recruit -arrestins, which regulate receptor trafficking and desensitization, and can also modulate downstream extracellular signal-regulated kinases (ERK1/2), thereby influencing -cell function in a context-dependent manner (28,29)