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A prespecified nephrology analysis showed a 22% relative risk reduction in the composite renal endpoint (new macro-albuminuria, doubling of serum creatinine, dialysis, or renal death) driven mainly by a 26% fall in new-onset macro-albuminuria [8, 36]

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Nauck et al ., 1997), promoting satiety (Turton et al ., 1996

Moreover, despite statistical significance, the improvements did not reach minimal clinically important difference (MCID) thresholds for all patients (Ghorbani et al., 2024)

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