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The integration of these targeted therapy agents approved by the FDA into clinical practice is certainly a step ahead in precision medicine in the treatment of cancer [ Figure 5 ] , for it enables the stratification of therapies according to tumor biology and optimizes treatment outcomes for unique types of breast cancer

Cancers feed off the fuel of bad metabolism, so if you improve that, you're actually going to help people.

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Activation of IGF-1R leads to the stimulation of two major downstream pathways, PI3K/AKT and Ras/ERK pathways