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Jim Eggeman, a 911 operator in Ohio, said that before taking semaglutide, I could sit down and eat a large pizza, and now its one to two pieces at the most. He started on the drug for diabetes after a heart attack in December 2019 and lost 35 pounds, bringing his weight to 220

Body composition and ectopic lipid changes with biochemical control of acromegaly

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The identification of exendin-4 from Gila monster (Heloderma suspectum) saliva as a stable GLP-1 mimetic enabled appetite suppression and glycemic control in metabolic disease, driving the development of long-acting GLP-1 analogues and unimolecular agents that co-activate GLP-1 and GIP receptors (Mller et al., 2025)

Open Heart, 2015

Avoid hot water, which further depletes barrier lipids