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Differentially expressed MCTs are crucial for the establishment and functioning of the glia-neuron metabolic interactions in health and disease
Glutathione is also the obligate substrate for glutathione S-transferases (GSTs), the enzyme family responsible for phase II hepatic detoxification conjugating GSH to electrophilic xenobiotics, heavy metals, and endogenous toxins to render them water-soluble and excretable
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5-HT derived from microbial tryptophan metabolism regulates neuronal and glial development through critical processes including cell proliferation, differentiation, and synaptogenesis (Gaspar et al., 2003)
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