While those numbers are worth noting, theyre comparable to or lower than what is observed with Semaglutide (which saw 7-11% discontinuation across trial arms) and suggest manageable tolerability for most participants
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By targeting these pathways, Zepbound not only helps control appetite and slow gastric emptying but also improves blood sugar regulation
By the end of the trial period, average results showed: Those on a 4 mg dose lost 47.2 pounds (lb), or about 19 percent of their starting body weight
Circulation 2024;150(22):1781-1790
Thus, less frequent and smaller meals are recommended, which would predispose patients to biliary sludge, gallstone formation and slowed biliary motility