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Purkinje cell collaterals enable output signals from the cerebellar cortex to feed back to Purkinje cells and interneurons

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It could be possible that Nlrp3 deficiency prevent cell response to sUA by removing the ability to produce ROS under stimulation

Western blot assays showed that no significant alteration in the expression of SLC7A11 was observed in VRK2-downregulating PC cells (Fig