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Ballard and colleagues (Growth Regulation, 1993) reported that native IGF-I binds IGFBP-3 with approximately one thousand times the affinity of LR3IGF-I

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Pirfenidone attenuates bleomycininduced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium

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In addition, this amino acid plays a role in protein turn-over and purine and pyrimidine synthesis 24,25