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Safety, efficacy, and cardiovascular benefits of combination therapy with SGLT-2 inhibitors and GLP-1 receptor agonists in patients with diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials

This results in reduced food intake, delayed gastric emptying, and improved satiety

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As GPX4 reduces phospholipid hydroperoxides, its dysfunction results in lethal lipid reactive oxygen species) ROS (accumulation ( Ferroptosis also interfaces with immune and inflammatory pathways