As with other GLP-1 medicines, they are generally not suitable for people with a personal or family history of medullary thyroid carcinoma or MEN2, and caution is needed in people with certain gastrointestinal issues, pancreatitis concerns, gallbladder disease, or other relevant medical conditions
[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Morgan B, Sobotta MC, Dick TP
Phentermine prescriptions usually come through an obesity medicine specialist or primary care clinician
NICE guidelines (NG28) support the use of GLP-1 receptor agonists for type 2 diabetes when glycaemic targets are not achieved with other therapies, and for weight management in specific circumstances (TA875 for Wegovy, TA664 for Saxenda)
Collectively, these results imply that the action of GLP-1R induced by GLP-1RAs cannot be attributed to one specific region of the brain but must be understood from a brain-wide perspective
Most of the GLP-1 drugs studied in this group, of which there are several, remain largely under patent protection