Depletion of resting zone chondrocytes during growth plate senescence
The SELECT trial, which followed over 17,000 participants, showed that 16.6% of semaglutide-treated patients discontinued due to adverse events compared to 8.2% on placebo
Do All GLP-1 Work the Same
Research in The New England Journal of Medicine found that people taking semaglutide (the active ingredient in Wegovy) lost an average of 15% of their body weight in a little over a year
Gray market products exist in an in-between space, since theyre not exactly illegal, but are obtained through channels that lack proper authorization for personal use, says Dr
From a dietary perspective, the following principles are recommended, consistent with the NHS Eatwell Guide: Eat regular, balanced meals do not skip meals, as this can worsen nausea and lead to overeating later Reduce portion sizes gradually the medication will help with satiety, but mindful eating remains important Limit ultra-processed foods, sugary drinks, and high-fat snacks these can exacerbate gastrointestinal side effects and undermine calorie reduction Prioritise protein and fibre these nutrients support satiety and help preserve lean muscle mass during weight loss Stay well hydrated aim for pale-yellow urine as a guide
