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As MASLD and hypertension are common co-morbidities, a study regarding differences in GSTM1 and GSTO1 protein expression in normotensive and hypertensive rats was performed which showed significant GSTO1 downregulation and no change in GSTM1 levels in hypertensive rats (Svoboda and Kawaja 2012)

Histological evaluation For liver pathological changes observation, the liver and epididymal adipose tissue in indicated groups were fixed with 4% paraformaldehyde, embedded, sectioned and cut into thin slices (5-m thickness)

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