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A separate product, semaglutide subcutaneous injection (Wegovy), is indicated as an adjunct to lifestyle modifications for weight loss and chronic weight management in obese (BMI 30 kg/m2 or greater) or overweight adults (BMI 27 kg/m2 or greater) with at least 1 weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia)

It has however been used for years and there are papers that have noted that there are no risks that would disallow the usage

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A spontaneous report cannot prove causation, but it is relevant to safety surveillance

Tirzepatide or Retatrutide, an alternative, NOT a combination Tirzepatide and Retatrutide are competing multi-receptor molecules

The impact of multifactorial stress combination on plant growth and survival