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Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

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Administration of Vitamin C and resveratrol effectively mitigated diazinon-induced liver damage, as shown by improvements in several key biochemical and histopathological examinations

Abbreviations PD : Parkinson Disease CoQ10 : Coenzyme-Q10 UPDRS : Unified Parkinson Disease Rating Scale ROS : Reactive oxygen species RNS : Reactive nitrogen species SUV : Small unilamellar vesicles TEM : Transmission electron microscopy XRD : X-ray diffraction OFT : Open field test SOD : Superoxide dismutase CAT : Catalase MDA : Malondialdehyde GSH : Glutathione PC : Protein content NO : Nitric oxide DPPH : 2,2-Diphenyl-1-picrylhydrazyl AChE : Acetylcholinesterase TH : Tyrosine hydroxylase DAT : Dopamine transporter GFAP : Glial fibrillary acidic protein References See, W.Z.C., R

ROS can activate MMPs (including MMP-2) and simultaneously decrease concentrations of TIMPs (including TIMP-2) and this can contribute to BBB permeability (68)

doi: 10.1159/000127099 76 KulikovAVJeanningroR