Gandoerma lucidum constituent ganoderic acid (GAB
Compound 5 was isolated by silica gel column chromatography using a dichloromethane/methanol (DCM:MeOH = 20:1, V/V) eluent (yield: 61%)
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Analysis of splenocytes demonstrated decreased CD4+IL-4+ and CD4+IL-17-secreting T cells when treated with high dose luteolin, which corresponded with the re-stimulation of splenocytes resulting in significant decreases in IL-4 expression [162]
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