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The current analysis showed consistent reductions with semaglutide in the risk of MACE versus placebo across baseline eGFR and UACR subgroups, which is in line with a meta-analysis that evaluated CVOTs showing that GLP-1RAs reduced the risk of MACE versus placebo, regardless of baseline eGFR [7]

The team randomly administered 8mg or 12mg of retatrutide to participants for eight months and tracked changes in liver fat levels

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Panopoulos, A.D., et al.,The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

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