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528 High ROS levels induce oxidative stress and potentially trigger -cell apoptosis, 529 undermining insulin secretion and blood sugar control

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(72) demonstrated, using a rat left coronary artery ligation model, that vitexin reduced MDA levels in cardiomyocytes while increasing SOD and NADPH activities, thereby inhibiting lipid peroxidation, preventing cardiomyocyte ferroptosis, and improving cardiac function