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Patients typically report decreased cravings and compulsive behaviors within 2-4 weeks

Malignant melanotic Schwannian tumor: a clinicopathologic, immunohistochemical, and gene expression profiling study of 40 cases, with a proposal for the reclassification of melanotic schwannoma"

PMID 15483230

The suspected mechanism is glucagon activity: the glucagon receptor is expressed in certain tissues of the peripheral nervous system, and its chronic activation appears to alter neurosensory signaling in some subjects