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There is also a trial specifically testing whether retatrutide prevents heart attacks and strokes (TRIUMPH-3, 1,800 people), and a head-to-head trial comparing retatrutide directly against tirzepatide (the active ingredient in Zepbound) under identical conditions (NCT06662383, 800 patients)

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People with diabetes also need medication review because insulin, sulfonylureas, and appetite changes can interact in clinically important ways

Consistent dosing is one of the simplest ways to support reliable results

Stevanato estimates that oral GLP-1s will capture a 30% market share by 2030, though precise forecasting remains elusive

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