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10.1152/ajpcell.1990.259.1.C3 226

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As anticipated, arginine can be converted to nitric oxide by NOS (from the citrulline cycle) or directed to the mitochondria, where it is catabolized by arginase 2 to urea and ornithine (urea cycle)

Altered differentiation in rat and rabbit limb bud micromass cultures by glutathione modulating agents

A separate analysis in Nature Medicine found that retatrutide produced significant reductions in liver fat content in participants with metabolic dysfunction-associated steatotic liver disease (MASLD), suggesting benefits beyond simple weight reduction