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Entre las vas activadas figuran las implicadas en la reparacin tisular, la defensa antioxidante (a travs de la superxido dismutasa y la glutatin peroxidasa), y la sntesis de componentes de la matriz extracelular

Journal of Physiology-Paris 87:313327 Sikiric P, Rucman R, Turkovic B, Sever M, Klicek R, Radic B, Drmic D, Stupnisek M, Misic M, Vuletic LB, Pavlov KH (2018) Novel cytoprotective mediator, stable gastric pentadecapeptide BPC 157

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PubMed Central , doi:10.1161/JAHA.115.002621

This is the mechanism that makes TB-500 relevant to injuries that involve slow or stalled healing: when the local repair response has exhausted its resources, TB-500 recruits fresh cells from the surrounding tissue and circulatory system into the damage zone

Iconic sites include the Puno Cathedral, a Baroque-style Andean construction, and the 19th-century Yavar steamship (currently operating as a hostel)