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doi: 10.1111/j.1742-4658.2008.06496.x 63 YaoG

Canonical HO-1 localises in the endoplasmic reticulum (ER) but the enzyme has been found to localise in other subcellular compartments including mitochondria, vacuoles, nucleus and plasma membrane

10.1186/s12889-021-12383-3 BMC Public Health

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Peptides stimulate growth factors, encourage collagen production, and recruit stem cells to areas of injury

Soon after stimulation by an appropriate triggere.g., chemokines/cytokines, pathogen components like lipopolysaccharide (LPS), and/or wounded tissueneutrophils migrate to areas of injury and/or infection and mount an initial innate immune response which requires a rapid metabolic switch dependent on G6PD